Table 3.

Immunosuppression and adjunctive treatment

Variable	High-dose prednisone n = 39	First-line CNI n = 11	Rescue CNI n = 16	P value
Prednisone
Months on prednisone	13 (7–22)	8 (6–12)	24 (12–28)	<0.001
Cumulative prednisone, g	9.3 (7.5–12.5)	2.5 (1.8–3.1)	13.8 (9.2–15.8)	<0.001
Cumulative prednisone, mg/kg	134 (112–180)	36 (26–39)	177 (145–209)	<0.001
Months to taper <10 mg	7 (6–12)	6 (4–7)	11 (6–18)	0.003
Calcineurin inhibitor
Tacrolimus	—	5 (45.5)	8 (50.0)	0.816
Avg plasma level, ng/dl	—	5.2 (4.0–7.9)	5.8 (4.4–7.3)	0.698
Cyclosporine	—	6 (54.5)	8 (50.0)	0.816
Avg plasma level, ng/dl	—	134 (92–186)	128 (92–172)	0.771
Months on CNI	—	12 (6–16)	16 (9–25)	0.174
Adjunctive treatment
RAAS blockade	33 (84.6)	9 (81.8)	15 (93.8)	0.596
Statins	21 (53.8)	5 (45.5)	10 (62.5)	0.676

Avg, average; CNI, calcineurin inhibitor; RAAS, renin−angiotensin−aldosterone system.