Table 4.
Cox regression analysis for factors associated with progression to end-stage renal disease
| Variable | Univariate |
Multivariate |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age, per yr | 0.979 | 0.934–1.026 | 0.373 | — | — | — |
| Male gender, versus female | 0.588 | 0.176–1.967 | 0.389 | — | — | — |
| Creatinine, per mg/dl | 1.622 | 1.064–2.474 | 0.025 | — | — | — |
| Proteinuria, per g/g | 1.111 | 0.992–1.244 | 0.070 | 1.259 | 1.052–1.507 | 0.012 |
| Chronicity score, per point | 1.510 | 1.122–2.033 | 0.007 | 1.558 | 1.052–2.305 | 0.027 |
| Response to treatment | ||||||
| No response | 1.000 | Ref | Ref | 1.000 | Ref | Ref |
| Partial response | 0.214 | 0.060–0.768 | 0.018 | 0.356 | 0.077–1.652 | 0.187 |
| Complete response | 0.026 | 0.003–0.220 | 0.001 | 0.023 | 0.001–0.212 | 0.002 |
CI, confidence interval; HR, hazard ratio; Ref, reference.