Figure 1.

The expression of SCC-S2 in CRC specimens and cell lines. SCC-S2 showed weak expression in normal colonic tissues (A), however, it showed strong cytosolic expression in tubular adenocarcinoma (B) and mucinous adenocarcinoma (C). The expression of SCC-S2 was remarkably higher in CRC specimens than that in noncancerous mucosa (D). Kaplan–Meier survival analysis revealed that the overall survival (OS) for patients with positive SCC-S2 expression was significantly shorter than those with negative SCC-S2 expression (E). As indicated in the figures, SCC-S2 was highly expressed in three of four CRC cell, while showed weak expression in SW480 cells (F). Scale bar = 50 μm, insert scale bar = 20 μm. Abbreviation: GAPDH, glyceraldehyde 3-phosphate dehydrogenase.