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. 2018 Dec 28;19(Suppl 17):493. doi: 10.1186/s12859-018-2461-2

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Differential network estimated by different methods. Orange edges show an increase in conditional dependency from control group to lung cancer patient group; grey edges show a decrease. Red points stand for hub genes which have edges with more than 3 other genes. a C-RDN. b B-RDN. c DDN