Table 5.

Gene Ontology (GO) enrichment analysis result

ID	Functional term	Ontology	Adjust P-value
			C-RDN	B-RDN	DDN
GO:0016055	Wnt signaling pathway	BP	1.69×10−11	2.96×10−6	0.0022
GO:0198738	cell-cell signaling by wnt	BP	1.69×10−11	2.96×10−6	0.0022
GO:0060828	regulation of canonical Wnt signaling pathway	BP	1.49×10−9	0.0012	0.0027
GO:0060070	canonical Wnt signaling pathway	BP	4.78×10−9	0.0012	0.0027
GO:0030111	regulation of Wnt signaling pathway	BP	6.67×10−9	0.0058	0.0091
GO:0005109	frizzled binding	MF	5.28×10−5	0.0058	0.0091
GO:0007369	gastrulation	BP	0.0024	0.0058	0.0276
GO:0017147	Wnt-protein binding	MF	0.0025	0.0073	0.0286
GO:0060562	epithelial tube morphogenesis	BP	0.0068	0.0073	0.0290
GO:0003002	regionalization	BP	0.0074	0.0080	0.0331
GO:0035239	tube morphogenesis	BP	0.0082	0.0090	0.0332
GO:0001503	ossification	BP	0.0093	0.0131	0.0341
GO:0007389	pattern specification process	BP	0.0113	0.0131	0.0357
GO:0043393	regulation of protein binding	BP	0.0202	0.0175	0.0377
GO:0034329	cell junction assembly	BP	0.0205	0.0178	0.0382
GO:0030877	beta-catenin destruction complex	CC	0.0223	0.0377	0.0382
GO:0045216	cell-cell junction organization	BP	0.0229	0.0409	0.0402
GO:0034330	cell junction organization	BP	0.0259	0.0411	0.0408
GO:0071496	cellular response to external stimulus	BP	0.0281	0.0411	0.0418
GO:0071214	cellular response to abiotic stimulus	BP	0.0290	0.0421	0.0448
GO:0104004	cellular response to environmental stimulus	BP	0.0290	0.0450	0.0453
GO:0051098	regulation of binding	BP	0.0330	0.0474	0.0478
GO:0045992	negative regulation of embryonic development	BP	0.0341	0.0479	0.0495
GO:1903829	positive regulation of cellular protein localization	BP	0.0397	0.0489	0.0495
GO:1901990	regulation of mitotic cell cycle phase transition	BP	0.0409	0.0489	0.0498

BP: biological process; MF: molecular function; CC: cellular component