Table 1.
Plant extract | Oxytosis EC50(µg/ml) | BV-2 cells EC50(µg/ml) | PC12 cell differentiation | % Decrease in cell number at EC50 |
---|---|---|---|---|
A | 16.5 | 50 | yes | 10 |
B | 53 | 85 | no | 0 |
C | 20 | < 25 | yes | 9 |
D | 14 | 103 | no | 1.5 |
E | 43 | 179 | no | 4 |
F | 18 | < 25 | yes | 17 |
G | 3 | < 25 | yes | 8 |
H | 8.3 | 22.5 | yes | 25 |
I | 32 | 62.5 | no | 20 |
The results for the 9 most potent plant extracts in the primary screen (oxytosis assay using HT22 cells) as well as the BV-2 cell assay for anti-inflammatory activity and the PC12 cell differentiation assay. The effects of the extracts on the HT22 cell number was also determined. EC50 = half maximal effective concentration.