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. 2018 Dec 21;12:325. doi: 10.3389/fnbeh.2018.00325

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Copyright © 2018 Scheimann, Mahbod, Morano, Frantz, Packard, Campbell and Herman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dlx5/6 GRKD mice show glucocorticoid receptor (GR) knockdown (KD) in most Gad67+ cells. (A) Representative image of a control (Dlx5/6 Cre-; GR f/f) mouse prefrontal cortex (Prelimbic PFC) showing GR staining in Gad67 cells. (B) Representative image of a Dlx5/6 GRKD (Dlx5/6 Cre+; GR f/f) mouse PFC (Prelimbic PFC) showing little to no GR staining in Gad67 cells. (C) Dlx5/6 GRKD mice have significantly fewer cells with definitive GR staining in the Prelimbic. *p ≤ 0.05.