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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Neuropharmacology. 2018 Sep 7;141:260–271. doi: 10.1016/j.neuropharm.2018.09.005

Figure 5. DiR agonist-induced AIMs: MMP-2200 has no effect on LAO AIMs, but significantly reduces locomotor AIMs.

Figure 5.

(A) Mean total LAO AIMs scores (± SEM) are plotted. MMP-2200 (20 mg/kg, i.p.) had no effect on the SKF81297 (0.8 mg/kg, s.c.)-induced LAO AIMs. (B) Mean total locomotor AIMs scores (± SEM) are graphed; a reduction of SKF81297- induced locomotor AIMs by MMP-2200 is evident. (C) The graph shows the time-course of action of MMP-2200 on DiR agonist-induced LAO-AIMs. (D) The graph depicts the time- course of the action of MMP-2200 on D1R agonist-induced locomotor AIMs. In all graphs, AIMs scores were acquired over a 180 min interval following administration of drugs, using a within-subjects crossover design (*p < 0.05; n = 8).