Fig. 4. Igf2 KO rescues Zfp568 KO–induced lethality.
(A) Relative Igf2-P0 levels in embryonic and extraembryonic tissues from E8.5 Zfp568-GFPFL/FL and Zfp568KO/KO littermate embryos. t test: Error bars indicate standard deviation; *P < 0.05; n = 3. (B) Bright-field and GFP-fluorescence images of Zfp568-GFPFL/FL and Zfp568KO/KO littermate embryos at E8.5. (C) Images of pups of indicated genotypes from Zfp568 KO and paternal (pat) Igf2 KO crosses at E18.5.