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. Author manuscript; available in PMC: 2020 Jan 2.
Published in final edited form as: Virology. 2018 Oct 31;526:146–154. doi: 10.1016/j.virol.2018.10.014

Fig. 6. Virus titers in tissue from 10-day-old mice infected with EV-D68 and treated with guanidine.

Fig. 6.

Mice (n = 5/group) were treated b.i.d. × 5 days beginning 4 h post-infection. Guanidine treatment at 100 mg/kg/day decreased virus tissue titers by at least 2-logs in all tissues that were evaluated. Reductions to virus titers in the spinal cord and brain are likely responsible for increases in survival. **P < 0.01, ***P < 0.001, ****P < 0.0001.