Table 4: Multivariate logistic regression models.
Odds ratio | 95% CI | P value | |
---|---|---|---|
Model 1 (DV: clinical diagnosis of PSP) | |||
Age at death, years | 0.99 | 0.92–1.05 | 0.651 |
Sex (0: female, 1: male) | 1.01 | 0.35–2.88 | 0.990 |
Disease duration, years | 0.95 | 0.80–1.12 | 0.523 |
Downward gaze palsy | 26.9 | 8.39–86.3 | 3.1×10−8 |
Asymmetric rigidity/apraxia | 0.27 | 0.08–0.87 | 0.028 |
Model 2 (DV: downward gaze palsy) | |||
Age at death, years | 1.02 | 0.97–1.08 | 0.385 |
Sex (0: female, 1: male) | 1.04 | 0.44–2.46 | 0.928 |
Disease duration, years | 0.88 | 0.73–1.06 | 0.181 |
TDP-43, midbrain tectum | 9.77 | 1.75–54.7 | 0.010 |
TDP-43, midbrain tegmentum | 0.79 | 0.31–2.02 | 0.618 |
Tau, oculomotor complex | 1.51 | 1.09–2.08 | 0.012 |
Tau, midbrain tectum | 0.79 | 0.59–1.06 | 0.120 |
TDP-43 and tau pathology are four-point scale (0: absent, 1: mild, 2: moderate, 3: severe). Abbreviation: DV, dependent variable; PSP, progressive supranuclear palsy.