Table 3.
Post Assessment Severity and Diagnostic Characteristics in PCIT-ED and Wait List Subjects Completing the Post Assessment
Wait List (N=91)
|
PCIT-ED (N=100)
|
Wait List vs. PCIT−ED
|
|||||||
---|---|---|---|---|---|---|---|---|---|
Primary Outcome: MDD Diagnosis | % | N | % | N | χ2 | p | FDR p | OR | 95% CI |
Major Depressive Disorder (or NOS) | 74.7 | 68 | 22.0 | 22 | 46.92 | <0.0001 | <0.0001 | 12.15 | (5.95, 24.82) |
Secondary Outcome: Remission | % | N | % | N | χ2 | p | FDR p | OR | 95% CI |
| |||||||||
Remission of MDD* | 23.1 | 21 | 73.0 | 73 | 42.86 | <0.0001 | <0.0001 | 0.10 | (0.05, 0.20) |
PFC−Scale reduced ≥50%, no MDD | 5.6 | 5 | 43.4 | 43 | 26.43 | <0.0001 | <0.0001 | 0.07 | (0.03, 0.20) |
Secondary Outcome: Severity | Mean | SD | Mean | SD | t | p | FDR p | Partial η2 | Cohen’s d |
| |||||||||
MDD core score | 4.15 | 2.04 | 1.74 | 1.69 | 9.11 | <0.0001 | <0.0001 | 0.31 | 1.02 |
PFC-Scale score | 33.20 | 11.10 | 20.10 | 9.65 | 9.44 | <0.0001 | <0.0001 | 0.33 | 1.11 |
Secondary Outcome: Severity | Mean | SD | Mean | SD | t | p | FDR p | Partial η2 | Cohen’s d |
| |||||||||
CGAS score | 55.75 | 17.14 | 76.83 | 16.61 | −8.62 | <0.0001 | <0.0001 | 0.29 | 1.16 |
PECFAS/CAFAS | 8.07 | 4.02 | 4.83 | 3.22 | 7.15 | <0.0001 | <0.0001 | 0.23 | 0.91 |
CGI-I score | 3.40 | 1.25 | 2.07 | 0.86 | 8.67 | <0.0001 | <0.0001 | 0.29 | 1.25 |
Mania/Hypomania | 0.0 | 0 | 0.0 | 0 | – | – | – | – | – |
Anxiety Disorder | 26.4 | 24 | 10.1 | 10 | 10.37 | 0.0013 | 0.0014 | 4.52 | (1.80, 11.31) |
ADHD (or NOS) | 22.0 | 20 | 13.1 | 13 | 1.50 | 0.2211 | 0.2211 | 1.72 | (0.72, 4.12) |
ODD (or NOS) | 38.5 | 35 | 14.1 | 14 | 16.95 | <0.0001 | <0.0001 | 5.95 | (2.55, 13.89) |
Conduct Disorder | 1.1 | 1 | 1.0 | 1 | – | – | – | – | – |
Cohen’s d is for the change from baseline to post; FDR = false discovery rate; OR = odds ratio;
Remission defined as not meeting diagnostic criteria for major depressive disorder and a 50% or greater reduction in MDD core score from baseline to post; Analyses covary for baseline characteristics, gender, and baseline externalizing disorder.