CD4+ activation was similar in the blood between cancer septic mice and previously healthy septic mice as measured by CD25+ (A, p=0.28) and CD69+ (B, p=0.43) cells. Similarly blood CD8+ activation was similar in the blood as measured by CD25+ (C, p=0.63) and CD69+ (D, p=0.43) cells. CD4+CD25+ cells were similar in the mesenteric lymph nodes between cancer septic mice and previously healthy septic mice (E, p=0.87) although CD4+CD69+ cells were higher in cancer/septic mice (F, p=0.02). No difference was detected in activation of CD8+ cells in the mesenteric lymph nodes whether measured by CD25+ (G, p=0.82) or CD69+ (H, p=0.43) cells, n=6–8/group for all panels.