Skip to main content
. Author manuscript; available in PMC: 2019 Apr 3.
Published in final edited form as: Nature. 2018 Oct 3;562(7727):444–447. doi: 10.1038/s41586-018-0587-z

Figure 2. Atomic models of Conformers 1 and 2.

Figure 2.

(a,b) Cryo-EM structures of the FimD-tip complex in Conformer 1 (a) and Conformer 2 (b), colored as in Fig. 1a. The dashed orange shape highlights the plug, which contacts the NTD in Conformer 2 but loses contact in Conformer 1 (see Extended Data Fig. 7). (c) Interactions between FimD N-tail and CTD2 in cartoon view. (d) Electron density for the FimD N-tail, with a local resolution of 4 Å. (e) FimD N-tail in cartoon view interacting with FimD CTD2 in surface-charge view, ranging from the blue positive to red negative charges.