Table 1.

Protein

Source	Model	Strain/ Species	Subject Sex	Diet Manipulation	Diet Exposure Period	Behavioral Assays	Testing Age	Significant Outcomes
Reyes-Castro 2012 (44)	Rat	Wistar	Male	10% protein (control 20%)	Gestation, Lactation, Perinatal	Open field test, Elevated plus maze	10 weeks	Gestational, lactational, and perinatal restriction impaired risk assessment (EPM).
Reyes-Castro 2012 (43)	Rat	Wistar	Female	10% protein (control 20%)	Gestation, Lactation, Perinatal	Open field test, Elevated plus maze, Operant conditioning & Progressive ratio	12-22 weeks	Perinatal and gestational restriction increased thigmotaxis (EPM, OFT), gestational restriction decreased motivation (PR).
Crossland 2017 (41)	Mouse	C57BL6/J	Male	8% protein (control 20%)	Pre-conception perinatal	Open field test, Elevated plus maze, Light/dark transition, Forced swim test, Tail suspension test, Fear conditioning	8-12 weeks	Increased thigmotaxis (EPM)
Belluscio 2014 (40)	Mouse	CF-1	Male and female	9% protein (control 20%)	Perinatal	Open field test, Elevated plus maze, Tail suspension test, Cage escape	3-9 weeks	Decreased motivation (CE), increased thigmotaxis and decreased rearing and head dipping (OFT, EPM). Increased behavioral despair in females only (TST).
Pillay 2016 (42)	Mouse	African Striped Mouse	Male and female	10% protein (control 19%)	Pre-conception perinatal	Open field test	10-11 weeks	Increased thigmotaxis (OFT)

Diet manipulation values presented as percent of g/kg. Abbreviations: EPM=Elevated Plus Maze, OFT=Open Field Test, PR=Progressive Ratio, CE=Cage Escape, TST=Tail Suspension Test