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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2018 Aug 13;32(1):68–78. doi: 10.1111/pcmr.12724

Fig. 2.

Fig. 2.

Naturally processed peptide elicits an IL17A response from SILv44-tranduced T cells. (A) IFN-γ secretion in response to HLA-A2+ melanocytes Mf0870 and Mf0626 does not differ significantly among PBMCs transduced to express the 3 TCRs. (B) Expression of T4H2 and R6C12 receptors trend towards greater IFN-γ secretion in response to melanoma cells. (C) IL-17A secretion, however, may be greater by SILv44-transduced T cells. (D) The trend observed in B is confirmed when comparing transduced T cells from 3 different donors responding to 888-A2+ cells. (E) Significantly greater IL-17A production observed among TCR transduced T cells from another 3 different donors responding to 888-A2+ cells.