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. Author manuscript; available in PMC: 2018 Dec 28.
Published in final edited form as: Environ Sci Technol. 2017 May 30;51(12):7091–7100. doi: 10.1021/acs.est.7b01172

Fig 1.

Fig 1.

Results of DT40 DNA-damage response bioassays on solvent extracts and fractionated extracts from PAH-contaminated soil used to feed a lab-scale bioreactor (“feed soil”, FS) and bioreactor-treated soil (TS). Assays were conducted with the parental DT40 cell line and two mutant cell lines deficient in different DNA-repair mechanisms, Rad54−/− and Rev1-/−. (A and B) LD50 values from the two fractions exhibiting measurable cytotoxicity (over the dose range tested) after the first level of extract fractionation. (C and D) LD50 values from the two subfractions of primary fraction B that exhibited cytotoxicity. Error bars represent standard deviations from replicates at each dose (n = 5). Asterisks indicate a significant difference between feed soil and bioreactor-treated soil for a given cell line. Plots of relative LD50 values corresponding to data in panels A-D are in Figure S2.