Table 3.
Pre- and Post-PAP use and outcomes by subgroups in patients with Overlap Syndrome.
| ER Visits | |||||||
|---|---|---|---|---|---|---|---|
| All Cause | COPD-related | ||||||
| One year pre-initiation of PAP | One year post-initiation of PAP | 1 P-Values | One year pre-initiation of PAP | One year post-initiation of PAP | 1 P-Values | ||
| Age group | 66–74 (N=173) | 92(53.18) | 88(50.87) | 0.59 | 28(16.18) | 26(15.03) | 0.71 |
| ≥75 (N=146) | 80(54.79) | 87(59.59) | 0.33 | 25(17.12) | 17(11.64) | 0.13 | |
| Low socioeconomic status | Yes (N=56) | 39(69.64) | 37(66.07) | 0.65 | 14(25.00) | 12(21.43) | 0.56 |
| No (N=263) | 133(50.57) | 138(52.47) | 0.59 | 39(14.83) | 31(11.79) | 0.23 | |
| Number of comorbidities | <3 (N=118) | 42(35.59) | 49(41.53) | 0.26 | 10(8.47) | 12(10.17) | 0.56 |
| ≥3 (N=201) | 130(64.68) | 126(62.69) | 0.63 | 43(21.39) | 31(15.42) | 0.07 | |
| Gender | Male (N=192) | 97(50.52) | 102(53.13) | 0.54 | 26(13.54) | 23(11.98) | 0.58 |
| Female (N=127) | 75(59.06) | 73(57.48) | 0.75 | 27(21.26) | 20(15.75) | 0.18 | |
| COPD complexity | Low (N=83) | 26(31.33) | 38(45.78) | 0.04 | 0 | 5(6.02) | - |
| Moderate and High (N=236) | 146(61.86) | 137(58.05) | 0.29 | 53(22.46) | 38(16.10) | 0.04 | |
| Hospitalization | |||||||
| All Cause | COPD-related | ||||||
| One year pre-initiation of PAP | One year post-initiation of PAP | 1 P-Values | One year pre-initiation of PAP | One year post-initiation of PAP | 1 P-Values | ||
| Age group | 66–74 | 84(48.55) | 79(45.66) | 0.51 | 47(27.17) | 39(22.54) | 0.19 |
| ≥75 | 69(47.26) | 67(45.89) | 0.80 | 34(23.29) | 23(15.75) | 0.07 | |
| Low socioeconomic status | Yes | 32(57.14) | 29(51.79) | 0.49 | 21(37.50) | 16(28.57) | 0.20 |
| No | 121(46.01) | 117(44.49) | 0.69 | 60(22.81) | 46(17.49) | 0.07 | |
| Number of comorbidities | <3 | 29(24.58) | 36(30.51) | 0.27 | 14(11.86) | 15(12.71) | 0.83 |
| ≥3 | 124(61.69) | 110(54.73) | 0.11 | 67(33.33) | 47(23.38) | 0.007 | |
| Gender | Male | 92(47.92) | 86(44.79) | 0.49 | 46(23.96) | 29(15.10) | 0.01 |
| Female | 61(48.03) | 60(47.24) | 0.88 | 35(27.56) | 33(25.98) | 0.72 | |
| COPD complexity | Low | 13(15.66) | 25(30.12) | 0.02 | 0 | 6(7.23) | - |
| Moderate and High | 140(59.32) | 121(51.27) | 0.04 | 81(34.32) | 56(23.73) | 0.003 | |
Definition of abbreviations: PAP = Positive Airway Pressure; ER = Emergency Room; COPD = Chronic Obstructive Pulmonary Disease.
1
P-values were generated from McNemar test.