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. Author manuscript; available in PMC: 2018 Dec 28.
Published in final edited form as: J Huntingtons Dis. 2018;7(1):35–50. doi: 10.3233/JHD-170266

Fig. 5.

Fig. 5.

Knockout of TRPC1 improves motor performance of YAC128 mice in the beam walk assay. (A) Average body weight of WT, YAC128+/−, TRPC1−/− and YAC128+/−TRPC1−/− mice at different ages. (B) Beam crossing latencies and (C) number of foot slips for WT, YAC128+/−, TRPC1−/− and YAC128+/−TRPC1−/− mice at ages 1.5–12 months for the 17 mm beam are shown as mean ± SE (WT, n=14 female mice; YAC128, n=14 female mice; TRPC1−/−, n=11 female mice; and YAC128+/−TRPC1−/−, n=11 female mice). *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 when the YAC128 group is compared to the WT group. #p<0.05, ##p<0.01, ###p<0.001, ####p<0.0001 when the YAC128 group is compared to YAC128+/−TRPC1−/− group.