. Author manuscript; available in PMC: 2020 Jan 1.

Published in final edited form as: J Vasc Surg. 2018 Aug 25;69(1):253–262. doi: 10.1016/j.jvs.2018.06.195

Table I:

Molecular markers of vessel identity arise early in embryogenesis.

Vessel	Marker	Embryologic day^*	Function
Vein	BRG1	9.0	Transcriptional Activator
	COUP-TFII	9.0	Transcription Factor
	Eph-B4	9.0	Membrane Receptor
Artery	VEGF-R2	7.0	Membrane Receptor
	Notch	7.5	Transcription Factor
	Ephrin-B2	8.5	Membrane Receptor
Lymphatic	Sox18	9.0	Transcription Factor
	Prox1	9.5	Transcription Factor
	VEGF-R3	8.5	Membrane Receptor

All embryologic times are derived from studies in mice and correspond to the embryologic day the marker is first detected.