Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Synthesis of prostaglandins. Arachidonic acid is metabolized by the cyclooxygenase enzymes sequentially to PGG2 and then PGH2. The individual prostaglandin synthases convert PGH2 into the five primary prostanoids, PGD2, PGE2, PGF2α, PGI2, and TXA2. Each of these prostanoids signal through distinct G protein coupled receptors (GPCR).
