Skip to main content
. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Pharmacol Ther. 2018 Aug 3;193:1–19. doi: 10.1016/j.pharmthera.2018.08.001

Figure 3.

Figure 3.

PGE2 signals through four GCPR, termed EP1, EP2, EP3, and EP4. Signaling through EP1 increases intracellular Ca2+, signaling through EP2 increases cAMP, signaling through EP3 decreases cAMP, and signaling through EP4 increases cAMP.