Effect of CP and A/S on GLT-1, xCT and GLAST expression in the nucleus accumbens (NAc). (A, C, E) Immunoblots for GLT-1/ β-tubulin, xCT/ β-tubulin and GLAST/β-tubulin, respectively. (B) Statistical analysis exhibited significant upregulation in the expression of GLT-1 in CP-A/S group as compared to CP-Vehicle and Vehicle-Vehicle groups. (D) Statistical analysis revealed significant downregulation in the expression of xCT in CP-Vehicle treated group as compared to Vehicle-Vehicle and CP-A/S groups. (F) GLAST expression was not changed among the treated groups in the NAc. (**p < 0.01 and ***p < 0.001), (n = 6-7 for each group), values shown as means ± S.E.M, (V: Vehicle; A/S: Ampicillin/Sulbactam; CP: CP 55,940).