Table 3.

Treatment efficacy according to initial regorafenib starting dose

Treatment outcomes	Total	80 mg (n=44)	120 mg (n=65)	160 mg (n=25)	P-value
PR	4 (3.0%)	2 (4.5%)	1 (1.5%)	1 (4.0%)
SD	37 (27.4%)	15 (34.1%)	18 (27.7%)	4 (16.0%)
PD	89 (66.4%)	26 (59.1%)	44 (67.7%)	19 (76.0%)
NE	4 (3.0%)	1 (2.3%)	2 (3.1%)	1 (4.0%)
Response rate	3.00%	4.50%	1.50%	4.00%	0.596
Disease control rate	30.40%	38.60%	29.20%	31.60%	0.299

Abbreviations: PR, partial response; SD, stable disease; PD, progressive disease; NE, not evaluated.