Table 3.

Summary of death and MI events among patients classified as low-risk by the HEART Pathway.

Age	Sex	Race*	Comorbidities	Site	HEAR score	0 hr cTnI ng/ml†	3 hr cTnI ng/ml†	Index Visit ED Disposition	Index Cardiac Testing	Event
41	Female	W	Hypertension Hyperlipidemia Diabetes Obesity Family history of early ACS	DMC	3	0.035	0.040	Transfer to WFBMC for admission	Coronary angiography; multivessel disease >70% stenosis	Index visit NSTEMI; troponin peak at 0.045 ng/ml. 3-vessel CABG during follow-up period
76	Female	AA	Hypertension, autoimmune hepatitis	WFBMC	3	0.007	<0.006	Discharged	None	Death on day 28; admitted to outside hospital for acute encephalopathy
57	Female	AA	Metastatic uterine cancer, DVT on Lovenox	WFBMC	3	0.011	0.033	Admitted to ICU, intubated for respiratory failure	None	Death during index hospitalization; care withdrawn
73	Male	W	COPD	WFBMC	2	<0.006	<0.006	Discharged	None	Death on day 6; Returned to ED with altered mental status from large subarachnoid hemorrhage
50	Male	AA	Hypertension, Tobacco, Cocaine abuse	WFBMC	3	0.007	0.017	Discharged	None	STEMI on day 12; Returned to ED with chest pain, ECG consistent with STEMI, coronary angiography with diffuse mild non-obstructive coronary artery disease (maximum stenosis = 25%)
43	Male	W	None	WFBMC	0	<0.006	<0.006	Admitted for hypoxemia and wheezing	None	Death during index visit, respiratory failure and PEA arrest

^*Race; W=White, AA= African American,

^†cTnI at WFBMC and DMC has upper reference limit and 99^th percentile value of 0.040 ng/ml and <10% coefficient of variation at 0.040 ng/ml. cTnI=cardiac troponin I, NSTEMI= non-ST segment elevation myocardial infarction, CABG= coronary artery bypass graft, DVT= deep vein thrombosis, ICU= intensive care unit, STEMI= ST segment elevation myocardial infarction, PEA= pulseless electrical activity.