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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Antiviral Res. 2017 Dec 14;150:93–100. doi: 10.1016/j.antiviral.2017.12.006

Table 11.

Among studies of immunological and non-immunological host factors, research on innate immune response to HBV infection was considered to be a top priority for discovering a cure for chronic hepatitis B.

Innate Immune Response
Project Rank
Comprehensive analysis of the hepatic innate and adaptive immune systems, and their roles in chronicity 1
How can understanding the innate and adaptive immune systems help in the therapeutic management of HBV? 1
Role of innate defenses in regulating HBV infection, and in pathogenesis 1
Specific innate host defense factors that are responsible for the role of the innate defense response in influencing HBV acute and chronic infections, and in HCC 2
Nature and mechanism of HBV refractoriness to type I IFN 2