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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Antiviral Res. 2017 Dec 14;150:93–100. doi: 10.1016/j.antiviral.2017.12.006

Table 4.

Research on the function of hepatitis B surface antigen was identified as a top priority for discovering a cure for chronic hepatitis B.

HBs
Project Rank
Determine and validate role(s) of HBs in hepatitis B chronicity and pathogenesis, including HCC and immunosuppression 1
Develop and validate antiviral agents that target HBs 1
Benefit of HBs as an antiviral target, alone or in combination 2
Determine detailed molecular mechanisms of HBs morphogenesis and role in virion production and secretion 2