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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Antiviral Res. 2017 Dec 14;150:93–100. doi: 10.1016/j.antiviral.2017.12.006

Table 5.

Research on the hepatitis B core protein was considered to be a secondary priority for discovering a cure for chronic hepatitis B.

HBc
Project Rank
Benefit as an antiviral target, alone or in combination 1
Development of antiviral agents that target HBc 1
Determine if HBc has regulatory functions for viral and cell genes 2
Determine HBc role(s) in HBV life cycle, pathogenesis, and immunomodulation, beyond its role as a structural component of the virus 2