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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Microbes Infect. 2018 Jun 26;21(1):50–55. doi: 10.1016/j.micinf.2018.06.003

Fig. 1. The cathelicidin peptide LL-37 is induced in the genital tracts of women with C. trachomatis infection.

Fig. 1

The remaining vaginal wash samples collected during previous studies were measured for LL-37 using ELISA. These wash samples had no identifiable patient information. Prior to the collection of vaginal wash with 50ml PBS from each woman, vaginal swabs were taken for diagnosing Chlamydia. Samples from 20 women diagnosed negative for C. trachomatis (Ct-, open bar) and 67 diagnosed positive (Ct+, solid bar) were used in the current experiment. Each sample was measured using neat solution in duplicate and the result was calculated into ng per ml of vaginal wash and displayed in mean plus/minus standard error from each group along the Y-axis. Note that women diagnosed positive for C. trachomatis produced significantly higher levels of LL-37 than those negative for C. trachomatis (**p<0.001, Wilcoxon Rank Sum).