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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Pain. 2019 Jan;160(1):117–135. doi: 10.1097/j.pain.0000000000001385

Figure 8. Treatment with BA does not affect Na+ currents in DRG sensory neurons.

Figure 8.

(A) Representative traces of Na + currents evoked from 200 millisecond prepulses between −70 mV and +60 mV with voltage protocol, illustrated from DRG sensory neurons treated with 0.1% DMSO or 20 µM BA. (B) Normalized current (pA/pF) versus voltage relationship of the sodium current density. (C) Scatter graph showing total peak Na+ current density at −10 mV (left bars) and TTX-sensitive Na+ current (right bars) (mean ± s.e.m.) from DRG sensory neurons treated with 0.1% DMSO (vehicle) or 20 µM BA (n = 8 cells per condition). No statistical significance was detected compared with cells treated with 0.1% DMSO (p>0.05, Mann-Whitney test). (D) Boltzmann fits for normalized conductance G/Gmax-voltage relations for voltage dependent fast-inactivation and activation of sensory neurons treated with vehicle or a 20 µM BA.