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. Author manuscript; available in PMC: 2019 Feb 28.
Published in final edited form as: Lab Invest. 2018 Jun 26;99(3):319–330. doi: 10.1038/s41374-018-0030-y

Figure 1. Volumetric assessment of lesion burden using micro-CT.

Figure 1

Cdh5iCreERT2 Krit1ECKO acute mice (n=10) had higher adjusted volume lesion burden than the acute PdgfbiCreERT2 Krit1ECKO (n=16), and the chronic Krit1+/−Msh2−/− (n=5). Pdcd10+/− Trp53−/− showed a significantly higher lesion burden than the non-sensitized PdgfbiCreERT2 Pdcd10ECKO (n=4) and Pdcd10+/− (n=21). All p values were considered to be statistically significant at *p<0.05, **p<0.01 or ***p<0.001.