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Acute Cdh5iCreERT2Krit1ECKO mice harbor proportionally more lesion within the cerebellum compared to chronic Krit1+/−Msh2−/− mice that have a more stochastic distribution (p<0.001). Example of a 3D rendering of an acute model (top) showing the highly-concentrated lesion burden in the cerebellum compared to the more stochastic distribution in a chronic brain model (bottom). All p values were considered to be statistically significant at ***p<0.001.
