Figure 3.
Ion mobility of native membrane-protein complexes. While these complexes all retain native oligomeric state, certain detergents favor lower charge states (top right of each panel) and minimal collisional cross sections consistent with X-ray crystal structures. Ion mobility mass spectrometry appears essential for true native MS. Reproduced from ‘Membrane proteins bind lipids selectively to modulate their structure and function. Arthur Laganowsky, Eamonn Reading, Timothy M. Allison, Martin B. Ulmschneider,Matteo T. Degiacomi, Andrew J. Baldwin, Carol V. Robinson. Nature 510, 172–175 (05 June 2014)’. Reprinted by permission from Macmillan Publishers Ltd: Nature (510, 172–175), copyright (2014) (https://www.nature.com/ncomms/).