Table 1:
Pre-operative Characteristics by Cohort
| Characteristics | Pre-Intervention | Intervention | ||||||
|---|---|---|---|---|---|---|---|---|
| Overall | STSnonMI | MI-Collaborative | p-value | Overall | STSnonMI | MI-Collaborative | p-value | |
| N | 196,954 | 189,774 | 7,180 | 714,800 | 690,605 | 24,195 | ||
| Demographics | ||||||||
| Age, mean (SD), y | 64.9 (10.5) | 64.9 (10.5) | 65.2 (10.5) | 0.109 | 65.2 (10.3) | 65.2 (10.3) | 65.6 (10.2) | <0.001 |
| Caucasian | 85.5 | 85.4 | 89.0 | <0.001 | 84.8 | 84.6 | 89.7 | <0.001 |
| Female | 26.1 | 26.1 | 26.5 | 0.38 | 24.8 | 24.8 | 25.2 | 0.190 |
| Laboratory Values | ||||||||
| Last Preoperative Hematocrit, mean (SD) | 38.5 (5.4) | 38.6 (5.4) | 38.3 (5.2) | 0.0007 | 39.2 (5.5) | 39.2 (5.5) | 39.1 (5.4) | 0.057 |
| Last White Blood Cell Count, mean (SD) | 8.2 (3.6) | 8.2 (3.6) | 8.0 (3.7) | <0.001 | 8.2 (3.3) | 8.2 (3.3) | 8.0 (3.1) | <0.001 |
| Comorbid Disease | ||||||||
| Dyslipidemia | 86.2 | 86.1 | 90.6 | <0.001 | 88.0 | 87.8 | 91.2 | <0.001 |
| Peripheral Arterial Disease | 14.3 | 14.2 | 17.1 | <0.001 | 14.2 | 14.2 | 16.0 | <0.001 |
| Cerebrovascular Disease | 14.1 | 14.0 | 15.9 | <0.001 | 18.6 | 18.5 | 21.8 | <0.001 |
| Diabetes Mellitus | 44.5 | 44.5 | 45.0 | 0.39 | 47.9 | 47.9 | 46.6 | <0.001 |
| Liver Disease | 2.2 | 2.2 | 2.2 | 0.96 | 3.0 | 3.0 | 3.3 | 0.0067 |
| Pulmonary Function | ||||||||
| Home Oxygen Therapy | 1.7 | 1.7 | 1.8 | 0.59 | 1.8 | 1.8 | 1.7 | 0.54 |
| History of Pneumonia | <0.001 | <0.001 | ||||||
| Recent | 2.9 | 2.9 | 2.9 | 2.9 | 3.0 | 2.4 | ||
| Remote | 3.4 | 3.3 | 5.0 | 4.1 | 4.0 | 5.7 | ||
| Current Cigarette User | 22.8 | 22.8 | 23.6 | 0.087 | 22.7 | 22.7 | 23.2 | 0.071 |
| History of Chronic Lung Disease | <0.001 | <0.001 | ||||||
| Unknown Severity | Not collected | Not collected | Not collected | 3.9 | 3.9 | 3.5 | ||
| Severe | 4.3 | 4.2 | 6.5 | 4.3 | 4.2 | 5.3 | ||
| Moderate | 6.2 | 6.1 | 6.4 | 5.3 | 5.3 | 5.6 | ||
| Mild | 13.5 | 13.4 | 17.3 | 11.5 | 11.3 | 16.9 | ||
| Cardiac Function | ||||||||
| Pre-operative Intra-aortic Balloon Pump | 10.2 | 10.3 | 8.3 | <0.001 | 9.6 | 9.6 | 7.9 | <0.001 |
| History of Arrhythmia | 12.7 | 12.7 | 13.6 | 0.021 | 13.5 | 13.4 | 14.9 | <0.001 |
| Ejection Fraction | 0.040 | 0.0002 | ||||||
| >=35 and <50 | 21.5 | 21.5 | 21.6 | 21.0 | 21.0 | 20.6 | ||
| <35 | 10.4 | 10.5 | 9.5 | 10.8 | 10.8 | 10.2 | ||
| Operative Status | <0.001 | 0.014 | ||||||
| Urgent | 56.0 | 55.9 | 61.2 | 57.6 | 57.5 | 59.8 | ||
| Emergent/Salvage | 4.9 | 4.9 | 3.5 | 4.6 | 4.6 | 2.8 |
Data are expressed as No. (%) unless otherwise indicated.
P-values are based on Pearson chi-square tests for all categorical row variables.
Unknown severity of history of chronic lung disease was not a category option in the Society of Thoracic Surgeons version 2.73, which was used in the pre-intervention period.