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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Semin Radiat Oncol. 2019 Jan;29(1):72–80. doi: 10.1016/j.semradonc.2018.10.005

Figure 2: GC4419 restores the migration ability of fibroblasts collected from elderly individuals to that of the ability of fibroblasts from young individuals.

Figure 2:

Exponentially growing young (5 month old foreskin) and old (78 year old male) human dermal fibroblasts were seeded in fibroblast basal media with growth factors. Cells were pre-treated for 24 hours with GC4419 (0.25 μM). Invading fibroblasts were stainedusing Thiazolyl Blue Tetrazolium Bromide (MTT) solution. GC4419 was able to restore the migration ability of fibroblasts from the 78 year old male to that of a 5 month old male.