Figure 1.
Hypnotic activation of α1(L264T)β3γ2 gamma-aminobutyric acid (GABA) type A receptors. A, Representative traces obtained by using a single oocyte on application of cyclopropyl-methoxycarbonyl metomidate (CPMM) at concentrations ranging from 0.1 to 100 μM. B, Representative traces obtained by using a single oocyte on application of propofol at concentrations ranging from 0.1 to 100 μM. C, Representative traces obtained by using a single oocyte on application of 100 μM CPMM in the absence or presence of 2 mM picrotoxin (PTX). D, Representative traces obtained by using a single oocyte on application of 100 μM propofol in the absence or presence of 2 mM PTX.