Figure 4. TEM imaging of antibody-targeted amph-NP uptake by CD8+ T cells.
T Cells were incubated with 80 µg/mL anti-CD8-conjugated amph-NPs (a, c, d) or unmodified amph-NPs (b) for 30 min after which were either fixed immediately (a-b) or incubated in serum-containing media (without NPs) for another 4 hours (c) or 24 hours (d) to allow for NP internalization and dispersion. Shown are representative TEM images of thin sections prepared from each timepoint.