TABLE 3.
Bivariate Analysis of Characteristics Associated With Mortality
| Variables | Mortality (n = 76) | Survived (n = 12,356) | OR (95% Cl) | p |
|---|---|---|---|---|
| Age (yr), n (%) | ||||
| <2 | 12(15.8) | 2,174(17.6) | 1.07 (0.48–2.40) | 0.862 |
| 2–5 | 12(15.8) | 2,334(18.9) | Reference | - |
| 6–12 | 13(17.1) | 1,113(9.0) | 2.27 (1.03–5.00) | 0.041 |
| 13–18 | 39 (51.3) | 6,735 (54.5) | 1.13(0.59–2.16) | 0.719 |
| Sex, n (%) | ||||
| Female | 41 (54.0) | 6,873 (55.6) | 0.94 (0.59–1.47) | 0.769 |
| Male | 35 (46.0) | 5,483 (44.4) | Reference | - |
| Race, n (%) | ||||
| White | 36 (54.6) | 6,351 (58.9) | Reference | - |
| Black | 9(13.6) | 2,022(18.8) | 0.79(0.38–1.63) | 0.518 |
| Hispanic | 10(15.2) | 1,121 (10.4) | 1.57 (0.78–3.18) | 0.206 |
| Other/mixed | 7(10.6) | 840 (7.8) | 1.47 (0.65–3.31) | 0.353 |
| Unspecified | 4(6.1) | 445 (4.1) | 1.59(0.56–4.48) | 0.384 |
| Intoxication type, n (%) | ||||
| Intentional | 59 (77.6) | 9,585 (77.6) | 1.00(0.58–1.72) | 0.990 |
| Accidental | 17(22.4) | 2,771 (22.4) | Reference | - |
| Multiple agent intoxication | 12(15.8) | 2,264(18.3) | 0.84(0.45–1.55) | 0.570 |
| PRISM III, median (IQR) (n = 11,392) | 22(12–30) | 0 (0–3) | 1.28(1.24–1.31) | <0.001 |
| PRISM III ≥ 10, n (%) | 63(85.1) | 470 (4.2) | 132.2(69.2–252.5) | <0.001 |
| Primary International Classification of Diseases, 9th Edition/drug classificationa, n (%) | <0.001 | |||
| Unknown | 7 (9.2) | 2,673(21.6) | ||
| Antidepressants | 4 (5.3) | 1,420(11.5) | ||
| Other chemicals | 17(22.4) | 1,312(10.6) | ||
| Analgesics | 4 (5.3) | 908 (7.4) | ||
| Antihypertensives | 1 (1.3) | 772 (6.3) | ||
| Opiates/opioids | 13(17.1) | 622 (5.0) | ||
| Alcohols | 1 (1.3) | 559 (4.5) | ||
| Nonsteroidal anti-inflammatory drugs | 0 (0.0) | 495 (4.0) | ||
| Antihistamines/antiemetics | 1 (1.3) | 405 (3.3) | ||
| Benzodiazepines/barbiturates | 2 (2.6) | 404 (3.3) | ||
| Stimulants | 4 (5.3) | 277 (2.2) | ||
| Antiepileptic drugs | 0 (0.0) | 275 (2.2) | ||
| Noningestions | 1 (1.3) | 270 (2.2) | ||
| Recreational drugs | 5 (6.6) | 252 (2.0) | ||
| Other pharmaceutical | 4 (5.3) | 233(1.9) | ||
| Alkalis/caustics | 0 (0.0) | 209(1.7) | ||
| Cardiac medications | 1 (1.3) | 184(1.5) | ||
| Insulin | 2 (2.6) | 167(1.4) | ||
| Maternal effect on fetus/newborn | 3 (4.0) | 153(1.2) | ||
| Muscle relaxants | 0 (0.0) | 150(1.2) | ||
| Sedatives | 1 (1.3) | 147(1.2) | ||
| Parasympatholytics | 0 (0.0) | 124(1.0) | ||
| Cough/cold medications | 0 (0.0) | 102 (0.8) | ||
| Carbon monoxide | 4 (5.3) | 62 (0.5) | ||
| Anti-infectives | 1 (1.3) | 60 (0.5) | ||
| Central nervous system depressants | 0 (0.0) | 53 (0.4) | ||
| Metals | 0 (0.0) | 45 (0.4) | ||
| Hormones | 0 (0.0) | 12(0.1) | ||
| Food | 0 (0.0) | 11 (0.1) | ||
IQR = interquartile range, OR = odds ratio, PRISM = Pediatric Risk of Mortality Score.
a
An odds ratio cannot be calculated due to some drug intoxications with no mortality reported.
Dashes indicate no p value for reference variables.