TABLE 4.

Multivariable Logistic Regression of Variables Associated With PICU Interventions^a (n = 11,392)

Variable	OR (95% Cl)	p
Pediatric Risk of Mortality Score III	1.30(1.26–1.34)	<0.001
Intoxication classification	46.56(16.73–129.57)	<0.001
Carbon monoxide	33.07(17.11–63.89)	<0.001
Alcohols	23.54 (10.86–51.04)	<0.001
Alkalis/caustics	17.42 (9.26–32.77)	<0.001
Maternal effects on fetus/newborn	12.08 (5.24–27.86)	<0.001
Metals	10.13 (4.60–22.30)	<0.001
Muscle relaxants	9.94 (4.55–21.69)	<0.001
Central nervous system depressants	9.26 (4.98–17.18)	<0.001
Other chemicals	8.61 (4.45–16.66)	< 0.001
Recreational drugs	7.15(3.63–14.10)	< 0.001
Antiepileptic drugs	6.54(1.12–38.25)	0.037
Food/plants	6.26(3.27–12.00)	< 0.001
Benzodiazepines/barbiturates unknown	5.86(3.18–10.80)	< 0.001
Opiates/opioids	5.72 (3.00–10.92)	< 0.001
Cough/cold medications	5.56(2.67–11.58)	< 0.001
Antihypertensives	5.55 (2.94–10.46)	< 0.001
Anti-infectives	5.52 (2.16–14.10)	< 0.001
Sedatives	5.11 (2.51–10.42)	< 0.001
Other pharmaceuticals	4.93 (2.61–9.33)	< 0.001
Antidepressants	4.88 (2.56–9.28)	< 0.001
Antihistamines/antiemetics	4.20 (2.27–7.78)	< 0.001
Stimulants	3.06 (1.62–5.77)	0.001
Cardiac medications	2.99 (1.41–6.34)	0.004
Hormones	2.87 (0.40–20.66)	0.295
Noningestions	2.54(1.03–6.24)	0.042
Analgesics	2.30(1.20–4.41)	0.013
Parasympatholytics	1.91 (0.80–4.52)	0.144
Nonsteroidal anti-inflammatory drugs	1.78 (0.98–3.25)	0.060
Insulin	Reference	–
Intentional intoxication	1.35 (1.12–1.62)	0.001
Multiple agent intoxication	1.08(0.97–1.21)	0.155
Gender (female)	0.82 (0.76–0.89)	<0.001
Age (yr)
<2	1.23 (1.01–1.50)	0.043
2–5	1.08(0.90–1.30)	0.400
6–12	Reference	–
13–18	1.36 (1.15–1.61)	<0.001

OR = odds ratio.

^aOnly mandatorily reported PICU interventions are included.

Boldface font indicates p < 0.05.