Table 2.

Serial analysis of plasma cytokines and chemokines

Cytokine or chemokine	Baseline	6 mo after SIV infection	P (baseline vs 6 mo)	12 mo after SIV infection	P (basleine vs 12 mo)
IL6	0.55 ± 0.33	1.33 ± 1.67	0.01	1.70 ± 1.83	0.0003
MCP1/CCL2	124.80 ± 60.86	167.43 ± 81.90	0.05	256.87 ± 278.88	0.0002
MDC/CCL22	246.53 ± 179.27	235.35 ± 167.42	0.86	341.33 ± 198.82	0.03
ITAC/CXCL11	5.93 ± 7.84	16.15 ± 15.05	0.02	23.14 ± 29.15	0.003
VEGF	0.17 ± 0.09	0.26 ± 0.21	0.04	0.24 ± 0.10	0.01
IP10/CXCL10	3.75 ± 2.64	5.17 ± 3.87	0.04	7.83 ± 7.57	0.02
IL10	1.59 ± 2.16	0.83 ± 0.68	0.2	0.88 ± 1.24	0.05
TNFα	5.51 ± 8.10	10.82 ± 23.17	0.49	10.69 ± 16.82	0.05
C-reactive proteina	5343 ± 2578	7601 ± 10826	0.81	27117 ± 33016	0.03
MIP1α/CCL3b	12.80 ± 9.69	16.15 ± 7.67	0.17	11.57 ± 7.85	0.76

CCL, C-C motif chemokine ligand; CXCL, C-X-C motif chemokine ligand; MCP, monocyte chemoattractant protein; MDC, macrophage-derived chemokine; MIP, macrophage inflammatory protein; CRP, C-reactive protein; IP, IFN-γ-inducible protein; ITAC, interferon-inducible T-cell α chemoattractant; VEGF, vascular endothelial growth factor

Data are given as mean ± 1 SD (pg/mL)

^aValues at 6 and 12 mo differ significantly (P = 0.02).

^bValues at 6 and 12 mo differ significantly (P = 0.01).