Table 1. Demographics, laboratory values, risk factors and liver disease characteristics of HCC patients with and without TIPS.
HCC-TIPS N = 37 |
HCC-No TIPS N = 242 |
p-value | |
---|---|---|---|
Age (IQR) | 62.03 [55.26, 65.52] | 60.75 [55.09, 66.40] | 1.000 |
BMI (SD) | 30.6 (6.0) | 27.6 (5.3) | 0.002 |
Male gender (%) | 25 (67.6) | 171 (70.7) | 0.849 |
Etiology of liver disease (%) | 0.050 | ||
ETOH | 13 (35.1) | 56 (23.1) | |
HBV | 2 (5.4) | 37 (15.3) | |
HCV | 13 (35.1) | 112 (46.3) | |
NASH | 5 (13.5) | 11 (4.5) | |
Other | 4 (10.8) | 26 (10.7) | |
Race (%) | 0.370 | ||
African American | 0 (0.0) | 9 (3.7) | |
Asian | 6 (16.2) | 60 (24.8) | |
Other/Unknown | 12 (32.4) | 72 (29.8) | |
White | 19 (51.4) | 101 (41.7) | |
Diabetes (%) | 19 (51.4) | 110 (45.5) | 0.62 |
Hypertension (%) | 22 (59.5) | 135 (55.8) | 0.81 |
Hyperlipidemia (%) | 12 (32.4) | 68 (28.1) | 0.73 |
Smoking (%) | 9 (24.3) | 75 (31.0) | 0.53 |
Family history of liver cancer (%) | 0 (0) | 6 (2.5) | 0.72 |
Ascites (%) | 30 (81.1) | 153 (63.2) | 0.052 |
Variceal Bleed (%) | 26 (70.3) | 65 (26.9) | <0.001 |
Hepatic Encephalopathy (%) | 30 (81.1) | 133 (55.0) | 0.005 |
Creatinine (mg/dL), IQR | 1.00 [0.74, 1.20] | 0.99 [0.80, 1.19] | 0.886 |
Bilirubin (mg/dL), IQR | 1.50 [1.10, 2.20] | 1.10 [0.70, 1.90] | 0.011 |
INR, IQR | 1.30 [1.20, 1.50] | 1.30 [1.10, 1.40] | 0.032 |
MELD, IQR | 14.00 [12.00, 16.00] | 13.00 [11.00, 16.75] | 0.099 |
AFP (ng/mL), IQR | 5.00 [3.00, 8.70] | 11.00 [5.00, 64.50] | 0.002 |
CTP score (median [IQR]) | 7.00 [6.00, 8.00] | 6.00 [6.00, 8.00] | 0.181 |