Fig 3. Variants in nucleotides and amino acids of the TTV7 determined by Sanger sequencing of individual Kawasaki disease (KD) patients.

Sanger sequencing was applied to TTV7 in KD patient seq. 1 (Table 1) and revealed variants in nucleotides (a), which resulted in amino acid changes (b). Similarly, TTV7 in KD patient seq. 5 harbored variants in nucleotides (c), which changed amino acids (d). The amino acid changes are identical between the two TTV7s. Spread sheet data is available in S2 Table. Splicing is not considered in the analysis of amino acid changes.