Treatment duration of brincidofovir (BCV). Horizontal bars depict individual patients. Black areas represent days of BCV monotherapy and white areas represent days of BCV with concomitant administration of acyclovir. Total BCV treatment days are calculated as the sum of individual patient-days on BCV monotherapy.
Two (6.7%, #12 and #28) patients developed breakthrough HSV infections. Breakthrough HSV/VZV infection was defined as any HSV/VZV infection that occurred on BCV or ≤7 days of BCV discontinuation.
BCV, brincidofovir; ACV, acyclovir; Cord, cord blood transplant; TCD, T-cell depleted transplant
* Breakthrough HSV infection on BCV.