(A) Discharge patterns of CA1 pyramidal cells (pyr) and interneurons (int) firing during awake SPW-Rs of different durations (black, blue, green, and red traces for progressively longer events). Note several “bumps” in the firing pattern of neurons during the longer-duration events (arrows).
(B) Same as in (A) but for CA3 pyramidal cells and interneurons.
(C and D) Distribution of the modulation strengths of (C) CA1 and (D) CA3 pyramidal cells and interneuron spikes by the CA1 pyramidal layer LFP phase in different frequency bands (5–300 Hz). Vertical dashed lines indicate boundaries of SPW, gamma, and ripple bands. Note that the unit-LFP modulation strength is lowest in the “gamma” band.
(E) Peri-SPW-R discharge patterns of entorhinal layer 2/3 excitatory cells (ECexc) during awake and sleep states. Note the additional firing rate peak prior to SPW-R onset appearing only for longest duration events during awake immobility (arrow).