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. Author manuscript; available in PMC: 2018 Dec 28.
Published in final edited form as: Arch Toxicol. 2014 Apr 8;88(8):1491–1502. doi: 10.1007/s00204-014-1234-6

Fig. 2.

Fig. 2

Metabolomics reveals the limitations for the in vivo application of GNF-351 due to poor absorption and high metabolism. The metabolic pathway was determined using UPLC-ESI-QTOFMS-based metabolomics. Red color highlights the drug-metabolizing enzymes regulated by Ahr