Table 3.
Risk factors for PTSD among survey respondents1
| Patient (n=691) | Caregiver (n=333) | |||||
|---|---|---|---|---|---|---|
| N | PTSD (%) | p value | N | PTSD (%) | p value | |
| Patient age at survey | ||||||
| ▓< 60 years | 302 | 14 (4.6) | 0.09 | 142 | 12 (8.5) | 0.24 |
| ▓≥ 60 years | 389 | 9 (2.3) | 191 | 10 (5.2) | ||
| Patient age at HCT | ||||||
| ▓< 18 years | 30 | 1 (3) | 10 | 20 (6.2) | 0.08 | |
| ▓> 18 years | 661 | 22 (3) | 323 | 2 (20.0) | ||
| Patient sex | ||||||
| ▓Female | 322 | 9 (2.8) | 0.47 | 146 | 9 (6.2) | 0.77 |
| ▓Male | 369 | 14 (3.8) | 187 | 13 (7.0) | ||
| Time since HCT1 | ||||||
| ▓≤ 5 years | 203 | 12 (5.9) | 0.01 | 134 | 12 (9.0) | 0.16 |
| ▓> 5 years | 488 | 11 (2.3) | 199 | 10 (5.0) | ||
| Type of transplant | ||||||
| ▓Auto | 230 | 8 (3.5) | 0.98 | 118 | 4 (3.4) | 0.13 |
| ▓Related allo | 253 | 8 (3.2) | 106 | 7 (6.6) | ||
| ▓Unrelated allo | 208 | 7 (3.4) | 109 | 11 (10.1) | ||
| Disease | ||||||
| ▓Acute myeloid leukemia | 133 | 8 (6.0) | 0.14 | 66 | 5 (7.6) | 0.67 |
| ▓Chronic myeloid leukemia | 112 | 0 | 35 | 3 (8.6) | ||
| ▓Myelodysplastic syndrome | 93 | 3 (3.2) | 47 | 5 (10.6) | ||
| ▓Multiple myeloma | 109 | 5 (4.6) | 67 | 4 (6.0) | ||
| ▓Lymphoma | 132 | 5 (3.8) | 72 | 4 (5.6) | ||
| ▓All others | 112 | 2 (1.8) | 46 | 1 (2.2) | ||
| Graft source | ||||||
| ▓Bone marrow | 220 | 4 (1.8) | 0.26 | 72 | 5 (6.9) | 0.72 |
| ▓Peripheral blood stem cells | 457 | 18 (3.9) | 252 | 17 (6.8) | ||
| ▓Cord blood | 14 | 1 (7.1) | 9 | 0 | ||
| Conditioning | ||||||
| ▓Myeloablative | 594 | 20 (3.4) | 0.89 | 270 | 15 (5.6) | 0.11 |
| ▓Non-myeloablative | 97 | 3 (3.1) | 63 | 7 (11.1) | ||
| Acute GVHD (allo only) | ||||||
| ▓0–1 | 179 | 4 (2.2) | 0.34 | 75 | 5 (6.7) | 0.5 |
| ▓2–4 | 285 | 11 (3.9) | 139 | 13 (9.4) | ||
| Chronic GVHD1 (allo only) | ||||||
| ▓Never | 169 | 5 (3.0) | 0.8 | 67 | 9 (13.4) | 0.14 |
| ▓≤ 5 years ago | 92 | 4 (4.4) | 59 | 5 (8.5) | ||
| ▓> 5 years ago | 200 | 6(3.0) | 89 | 4 (4.5) | ||
| Relapse1 | ||||||
| ▓Never | 641 | 23(3.6) | 0.4 | 309 | 18 (5.8) | 0.10 |
| ▓≤ 5 years ago | 16 | 0 | 10 | 2 (20.0) | ||
| ▓> 5 years ago | 34 | 0 | 14 | 2 (14.3) | ||
| Inpatient days2 | ||||||
| ▓≤ 35 days | 523 | 20 (3.8) | 0.27 | 274 | 18 (6.6) | 0.77 |
| ▓> 35 days | 151 | 3 (2.0) | 52 | 4 (7.7) | ||
1
All factors defined by patient except ‘time since’ factors
2
Divided on 75th percentile