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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: J Neurochem. 2018 Nov 26;147(6):784–802. doi: 10.1111/jnc.14582

Figure 3. TREM2 and TNF-α mRNA levels are altered in brains of HAND decedents on ART.

Figure 3

Total RNA was extracted from frontal cortex tissues, reverse transcribed to cDNA, and analyzed for (A) TREM2, (B) TNF-a, which was normalized to ACTB levels by rt2PCR. Fold-change compared to RNA extracted from an age-matched HIV- sample was calculated using the comparative CT method. Analyzed by two-way ANOVA; *p<0.05. (n=42, where n= the number of human specimens analyzed).