Table 2.
Placebo | p value | Car (6.25 mg) | p value | Car (12.5 mg) | p value | Car (25 mg) | p value | ||
---|---|---|---|---|---|---|---|---|---|
LVSd | Baseline | 28.0 ± 4.4 | 0.002 | 29.3 ± 4.4 | 0.059 | 29.2 ± 4.2 | 0.178 | 30.2 ± 5.7 | 0.458 |
6 months | 30.7 ± 5.7 | 30.4 ± 3.0 | 30.3 ± 4.3 | 30.9 ± 4.1 | |||||
LVDd | Baseline | 45.3 ± 5.3 | 0.566 | 46.0 ± 5.1 | 0.166 | 44.8 ± 4.3 | 0.011 | 44.6 ± 6.3 | 0.368 |
6 months | 45.9 ± 7.5 | 46.8 ± 4.0 | 46.0 ± 3.7 | 45.5 ± 5.3 | |||||
EF | Baseline | 62.0 ± 4.6 | 0.002 | 61.4 ± 3.9 | 0.059 | 60.0 ± 4.1 | 0.100 | 60.4 ± 4.2 | 0.073 |
6 months | 58.2 ± 6.6 | 60.0 ± 2.9 | 58.2 ± 6.6 | 59.2 ± 2.8 | |||||
E' | Baseline | 11.3 ± 3.0 | 0.365 | 11.9 ± 3.2 | 0.067 | 13.2 ± 5.0 | 0.001 | 11.8 ± 3.4 | 015 |
6 months | 10.9 ± 3.8 | 10.9 ± 3.4 | 11.8 ± 4.9 | 10.8 ± 3.0 | |||||
E/A | Baseline | 1.22 ± 0.4 | 0.533 | 1.20 ± 0.5 | 0.359 | 1.26 ± 0.5 | 0.949 | 1.17 ± 0.3 | 0.251 |
6 months | 1.20 ± 0.4 | 1.14 ± 0.4 | 1.27 ± 0.6 | 1.13 ± 0.3 | |||||
DT | Baseline | 190.7 ± 33.9 | 0.188 | 200.8 ± 28.2 | 0.637 | 203.6 ± 38.7 | 0.228 | 199.5 ± 38.8 | 0.139 |
6 months | 199.7 ± 39.8 | 197.1 ± 30.0 | 213.3 ± 45.1 | 209.3 ± 40.9 | |||||
E/E' | Baseline | 7.2 ± 2.6 | 0.413 | 7.4 ± 3.0 | 0.730 | 7.0 ± 3.3 | 0.033 | 6.9 ± 2.6 | 0.788 |
6 months | 7.6 ± 3.3 | 7.6 ± 3.6 | 8.0 ± 4.0 | 7.0 ± 2.2 |
Car* stands for carvedilol.