Table 6. Clinicopathologic characteristics of cases with mutation change in sequential analysis.

NAC=neoadjuvant chemotherapy; pCR=pathologic complete response; OS=overall survival; DFS=disease-free survival; cTN=clinical T&N stage; ypTN=post-NAC pathological T&N stage; HER2=human epidermal growth factor receptor 2; F/U=follow-up; i=isolated tumor cell; mi=microinvasion.

^*HER2 enriched: immunonistochemical stain for estrogen receptor and progesterone receptor (−); ^†NA: multiple distant metastases were found in the brain in this case, but further tests could not be performed because no samples were obtained; ^‡Luminal B: immunonistochemical stain for estrogen receptor or progesterone receptor (+).