Fig. 2.

The yeast p58C redox switch is mediated by conserved tyrosines. (Left) Bulk electrolysis and CV of WT yeast p58C. (Center) Bulk electrolysis and CV of p58C Y397F. (Right) Iterative electrochemical oxidation regenerates a CV signal on DNA. Cartoon (Bottom Right) Illustration of the electrochemically reversible redox switch in yeast p58C. All scans were performed anaerobically, on 30 μM [4Fe4S] p58C (WT, Y395F, or Y397F), 20 mM Tris, pH 7.2, 75 mM NaCl, 100-mV/s scan rate for CV. Illustration from ref. 9. Reprinted with permission from AAAS.